Technology
What NKEVs Are
Natural killer cell-derived extracellular vesicles should be described as biologically active vesicles derived from NK cell sources and developed as a therapeutic product candidate platform for oncology.
Mechanism
Vanquish’s platform is designed to combine direct tumor interaction with activation of the patient’s own NK-mediated immune response.
Product
Infusion-based product that can be shipped in powder form, formulated, and administered in conventional oncology care settings.
Framing
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Difficult-to-treat cancers
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Refractory settings
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Community-accessible administration model
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Lower infrastructure burden versus individualized cell therapy
Development and CMC
NK Cell Source → EV Isolation → Characterization → Formulation → Infusion Delivery
Process Development
Analytical Chemistry
Bioanalytical Validation
Scale-Up
Master Cell Bank
GMP-Readiness Planning